Searchable abstracts of presentations at key conferences in endocrinology

ea0029p698 | Diabetes | ICEECE2012

Relation between glucose daily profile (CGMS) and graft function after islet transplantation for type 1 diabetes mellitus

Vantyghem M. , Raverdy V. , Balavoine A. , Defrance F. , Caiazzo R. , Kerr-Conte J. , Hazzan M. , Pattou F.

Context: The influence of beta cell replacement on daily glucose profile in Type 1 diabetes mellitus (T1DM) is not firmly established.Objective: To examine the influence of islet transplantation (IT) on the various component of dysglycemia in T1DM patients.Design, setting and patients: Single arm open labeled study. Twenty-three consecutive patients with T1DM, 11 males and 12 females, 14 non uremic and 9 uremic with a previous kidn...

ea0032p562 | Endocrine tumours and neoplasia | ECE2013

Are hibernoma or lipoma a marker of type 1 multiple endocrine neoplasia (MEN1) aggressiveness?

Kamoun M , Karrouz W , Le Mapihan K , d'Herbomez M , Beron A , Caiazzo R , Porchet N , Pattou F , Wemeau J L , Vantyghem M C

MEN1, autosomal dominant, is characterized by combined tumours of the parathyroid glands, pancreatic islet cells, and the anterior pituitary, sometimes associated with other endocrine (adrenocortical, foregut carcinoid) and nonendocrine (lipoma, angiofibroma, collagenoma, ependymoma, meningioma) tumors. It is caused by inactivating mutations of the MEN1 tumour suppressor gene (chromosome 11q13), encoding menin. Menin, involved in activation of gene transcription, regu...